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Keto Chicken Enchilada Casserole

A hearty and satisfying low-carb casserole packed with flavors, perfect for weeknight dinners or gatherings.

By Shary Eliot ·APR 3, 2026 ·Updated OCT 1, 2026 ·Be the first to rate
Keto Chicken Enchilada Casserole
01Why this one

If you’re on a low-carb journey or simply looking for a hearty, satisfying meal, this Keto Chicken Enchilada Casserole is a game-changer! Packed with flavor and creamy goodness, it’s a fantastic option for weeknight dinners or when you’re hosting friends who might not even notice it’s keto-friendly. Trust me, once you try this dish, you’ll want to add it to your regular dinner rotation!

Why make this recipe

One of the standout features of this casserole is its versatility. Whether you’re cooking for a family that loves Mexican flavors or trying to impress a group of friends, this dish hits all the right notes. It’s quick to prepare, making it a perfect choice for busy weeknights or last-minute gatherings. Plus, with ingredients like chicken, cauliflower rice, and cheese, you can feel good about serving a meal that’s both delicious and low in carbs.

03At the stove

How to make Keto Chicken Enchilada Casserole

Creating this dish is straightforward, making it accessible even for novice cooks. The process involves mixing creamy ingredients, layering in your flavors, and baking until bubbly and golden. Here’s a quick look at what you can expect:

  1. Preheat your oven and prepare your baking dish.
  2. Combine cream cheese and sour cream for a rich base.
  3. Mix in the enchilada sauce and spices for that signature flavor.
  4. Stir in shredded chicken and cauliflower rice, then layer with cheese.
  5. Bake to perfection and garnish for a fresh finish.

Ingredients

What you’ll need

Gather these simple yet essential ingredients for a successful Keto Chicken Enchilada Casserole:

  • 1.5 lbs cooked chicken, shredded
  • 4 cups cauliflower rice, steamed and squeezed dry
  • 10 oz sugar-free red enchilada sauce
  • 4 oz diced green chilies, drained
  • 0.5 cup sour cream
  • 4 oz cream cheese, softened
  • 2 cups shredded Mexican blend cheese, divided
  • 1 tsp ground cumin
  • 1 tsp chili powder
  • 0.5 tsp garlic powder
  • 0.25 cup fresh cilantro, chopped

If you’re looking for substitutions, you can easily replace the cauliflower rice with riced broccoli for a different twist on texture and flavor!

Directions

Step-by-step instructions

  1. Preheat your oven to 375°F (190°C) and grease a 9×13 inch baking dish.
  2. In a large bowl, blend the softened cream cheese and sour cream until smooth.
  3. Stir in the enchilada sauce, drained green chilies, cumin, chili powder, and garlic powder until well combined.
  4. Add the shredded chicken and squeezed cauliflower rice, along with 1 cup of shredded cheese. Mix thoroughly to ensure everything is well coated in sauce.
  5. Spread the mixture evenly in your prepared baking dish.
  6. Top with the remaining 1 cup of cheese.
  7. Bake for 25 to 30 minutes, or until the casserole is bubbling, the cheese is golden brown and the center reaches 165°F (74°C).
  8. Allow to rest for 5 minutes, then garnish with fresh cilantro before serving.
Keto Chicken Enchilada Casserole
The recipe

Keto Chicken Enchilada Casserole

Rate it ·Dinner · Main Course · Low-Carb · Mexican
Prep
15 MIN
Cook
30 MIN
Total
45 MIN
Serves
8

01Ingredients

8 servings

Main Ingredients

02Method

  1. Preparation

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03Recipe notes

  1. 01This casserole is great with a fresh salad or sliced avocado. Consider serving with keto-friendly tortilla chips for added crunch. Best enjoyed hot, but delicious as leftovers too!

04Nutrition

Per serving
Calories
354
Protein
30G
Net carbs
5G
Fat
23G
Fiber
2G

Net carbs are total carbs minus fiber. Numbers are estimates from the ingredients listed.

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04After dinner

How to serve Keto Chicken Enchilada Casserole

Best ways to enjoy it

This casserole is delightful when served hot, but it’s also wonderful the next day! Pair it with a fresh salad or some sliced avocado for a complete meal. It also goes well with a dollop of Greek yogurt or extra cilantro to enhance those delicious Mexican flavors. If you want to make it even more festive, consider serving it with keto-friendly tortilla chips for added crunch.

How to store

Keeping leftovers fresh

If you have any leftovers (which might be a challenge!), store them in an airtight container in the refrigerator for up to 3 days. To reheat, simply pop it in the microwave or place it in the oven until warmed through. For longer storage, consider freezing the casserole before baking. Just be sure to cover it well, and it can last for about 2-3 months in the freezer.

Variations

Creative twists

If you’re looking to switch things up, here are a few variations to consider:

Different Proteins
Try substituting the chicken with ground turkey or shredded beef for a new flavor profile.
Cheese Swaps
Use pepper jack cheese for an extra kick, or go for a blend with a bit of cheddar for a different taste.
Add Vegetables
Incorporate veggies like bell peppers or zucchini for added nutrition and flavor.

FAQs

How long does it take to prepare?

The entire process takes about 15 minutes to prepare and around 30 minutes to bake.

What can I use instead of cauliflower rice?

You can replace cauliflower rice with riced broccoli or even shredded zucchini for a similar texture.

Can you freeze leftovers?

Yes, this casserole freezes very well! Just ensure it’s in an airtight container, and it can be stored for up to 2-3 months.

Conclusion

Keto Chicken Enchilada Casserole is not just another dinner option; it’s a cozy dish that brings family and friends together over delicious flavors. Ready to try it? Make sure to check out additional recipes for inspiration, such as this Keto Enchilada Casserole or explore the tasty twist on chicken in this bariatric low-carb chicken enchilada casserole. Enjoy cooking and savor every bite!

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